Design of Experiments (DOE)

ISO 13485, medical devices, medical device manufacturing, design of experiments

Q: I am looking for research articles or review papers on Design of experiments (DOE) specially focused on Response surface methods, Split Plot designs, MANOVA, and Repeated measures designs and analysis.  Any help to locate these articles will be greatly appreciated.

A: Thank you for contacting ASQ and the Quality Information Center. I received your request for articles on the topic of Design of experiments (DOE).  Design of experiments is defined as “a method for carrying out carefully planned experiments on a process.  By using a prescribed plan for the set of experiments and analyzing the data according to certain procedures, a great deal of information can be obtained from a minimum number of experiments” (from The Quality Toolbox, 2nd Ed. by Nancy R. Tague, Quality Press, 2005).

I searched the ASQ Knowledge Center for articles that focus on the specific areas you mentioned you were interested in.  I pulled some articles from my search results and have listed them below.  I have also included a link to the full search results so that you can take a look at all of the articles I found.

Response Surface Methods articles (Here is the link to the search results I received):

Split Plot Designs: (Full search results)

MANOVA: (Full search results)

Repeated Measures designs and analysis: (Full search results)

I hope that this information is helpful.  Please let me know if you have any questions or if you need additional assistance.

Best regards,

ASQ Research Librarian
Milwaukee, WI